(Note: This is not something that can be treated with drugs known as “blood thinners.”) Kidney problems Removing the protein from the blood using a procedure called plasmapheresis can rapidly reverse this problem. Patients with these symptoms should call their doctor. Symptoms of a stroke, like weakness on one side of the body and slurred speech.It can slow blood flow to the brain and cause: In some patients, large amounts of myeloma protein can cause the blood to “thicken.” This thickening is called hyperviscosity. This is also called peripheral neuropathy. This damage can lead to weakness and numbness and sometimes a “pins and needles” sensation. Sometimes, the abnormal proteins produced by myeloma cells are toxic to nerves. If spinal cord compression is not treated right away, there is a possibility of permanent paralysis. This is a medical emergency and you should contact your doctor right away or go to the emergency room. Muscle weakness, most often in the legs.This is called spinal cord compression and can cause If myeloma weakens the bones in the spine, they can collapse and press on spinal nerves. If the level of calcium gets high enough, you can even slip into a coma. Kidney problems and even kidney failure.Extreme thirst, leading to drinking a lot.High levels of calcium in the blood (called hypercalcemia) can cause: Thrombocytopenia: When blood platelet counts are low which may cause serious bleeding even with minor scrapes, cuts, or bruises.Leukopenia: Too few white blood cells that can lower resistance to infections such as pneumonia.Anemia: A reduced number of red blood cells that can cause weakness, a reduced ability to exercise, shortness of breath, and dizziness.Shortages of red blood cells, white blood cells, and blood platelets are common in multiple myeloma and might lead to other symptoms. Broken bones (fractures), sometimes from only a minor stress or injury.Bone weakness, either all over (osteoporosis), or where there is a plasmacytoma.Bone pain, which can be in any bone, but is most often in the back, the hips, and skull.Others can have common symptoms of the disease including: Bone problems
Some patients with multiple myeloma have no symptoms at all.
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